Leiomyosarcoma metastatic to the brain: CT features and review.

Leiomyosarcoma is an uncommon tumor that rarely metastasizes to the brain. It has been suggested that improved chemotherapy-resulting in improved survival rates-may have changed the metastatic pattern of this tumor, with an increasing frequency of cerebral metastasis. We present two histologically proven cases of leiomyosarcoma, one with a metastatic lesion in the cerebrum and the other in the cerebellum. In both cases, the metastatic lesion was of uniformly high attenuation on CT and demonstrated remarkable homogeneous enhancement. These findings are nonspecific, and are similar to those seen in meningioma. Cerebral angiography was of considerable value in one of the cases by helping to define intraaxial location of the tumor.